|Occupation: Tire shop owner|
|First Appearance: Cars 2 (2011)|
|Voiced by: Franco Nero|
Uncle Topolino is Luigi's uncle.
Luigi's favorite uncle, Uncle Topolino, lives in the small village of Carsoli, near Porto Corsa, Italy. He owns the village's tire shop, "Topolino's Tires", where he taught Luigi and Guido everything they know about tires.